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May 17, 2012 ... The effectiveness of clopidogrel is dependent on its activation to an active metabolite by the cytochrome P450 (CYP) system, principally ...
Dec 22, 2008 ... BACKGROUND: Clopidogrel requires transformation into an active metabolite by cytochrome P-450 (CYP) enzymes for its antiplatelet effect.
BACKGROUND: We sought to determine whether a 600-mg loading dose of clopidogrel reduces myocardial infarct size compared with a 300-mg dose using ...
May 9, 2012 ... Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. James SK, Storey ...
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Oct 6, 2010 ... Clopidogrel with or without omeprazole in coronary artery disease. Bhatt DL, Cryer BL, Contant CF, Cohen M, Lanas A, Schnitzer TJ, Shook TL, ...
JACC Cardiovasc Interv. 2008 Dec;1(6):620-7. doi: 10.1016/j.jcin.2008.09.008. The pharmacogenetics and pharmacodynamics of clopidogrel response: an ...
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Structure, classification, information, physical and chemical properties for Plavix, ( S)-Clopidogrel, Clopidogrelum, Zyllt, (+)-Clopidogrel, Clopidogrel (TN), ...
Abstract—The thienopyridines ticlopidine and clopidogrel are inhibitors of platelet function in vivo. Their mode of action has not been defined, but it appears that ...
Nov 17, 2011 ... Clopidogrel, the chemical name for Plavix, is an anti-platelet medication used to reduce the risk of heart attacks and strokes in individuals with ...
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